Immunology Assays that model the Tumour Microenvironment

We develop assays that generate functional, human‑relevant data to clarify mechanism of action, differentiate candidates, and uncover drivers of response or resistance.

  • Physiologically relevant in vitro immunology assays that model immune–tumour interactions in the TME
  • Our in vitro assay systems support a wide range of modalities (including BiTEs, ADCs, CAR‑T)
  • We integrate primary human immune cells (recallable PBMC donors) and/or engineered reporter cell lines with tumour targets

RoukenBio Immunology Assay Capabilities brochure

In vitro Assay Development across various Immune Cells

 Using our 10+ years of  immuno-oncology expertise, we have developed an array of in vitro assay systems that aim to replicate the complex immune cell interactions in the TME as accurately as possible. With a strong focus on novel and emerging therapeutic classes that are designed to modulate these processes, our assay platforms are applicable to immuno-oncology, auto-immunity, inflammation and beyond. 

t-cell-assays

T cell assays

b-cell-assays

B cell assays

macrophage-assays

Macrophage assays

nk-cell-assays

NK cell assays

dendritic-cell-assays

Dentritic cell assays

neutrophil-assays

Neutrophil  assays

basophil-cell-assays

Basophil assays

granulocytes

Granulocyte assays

Discover our extensive suite of T cells assays

T cells play a critical role in immune‑mediated tumour killing and response modulation. Their specificity, functionality and memory make them prime targets for immunotherapies.

Our T cell assays provide detailed insight into activation, function and engineering.

Download our technical slide deck to see real immunology assay data.

In our slides we cover:
- T cell Activation assays
- T cell Dependent Cellular Cytotoxicity (TDCC) assays
- T cell polarisation
- Antigen-specific recall
- MLRs (one-way and two-way)
- Gamma-Delta T cell assays
- CAR T cell engineering

T cell immunology assay development services RoukenBio

Why choose RoukenBio for immunoassay development?

Translational Focus

Off-the-shelf doesn’t cut it in I-O. Partner with experts in immuno-oncology to build custom assay systems using human primary cells in disease-relevant settings giving you the insight and edge to push innovation forward.

Rapid Turnaround. Relentless Quality.

We combine industry-leading turnaround times with a commitment to scientific excellence. Give us a problem, and we’ll find your solution.

10+ Years of Experience in Novel Cancer Immunotherapies

Grounded in experience and driven by curiosity, our brilliant minds work closely with our partners to deliver impactful science.

Explore RoukenBio's diverse in vitro immunoassay services

We aid drug developers by delivering human-relevant immuno-oncology assays from early drug discovery through IND-enabling stages. Our immuno-oncology therapeutic development services combine translational immunology, advanced primary cell systems and bespoke cell engineering to generate meaningful data across a wide range of therapeutic modalities.

Simply click on your selected flyers to download further information on our most popular assay models:

Can't find what you're looking for? At RoukenBio, we push the boundaries of immunological research and advance new therapeutic targets and modalities. Our passionate team combines scientific excellence with innovative thinking to turn complex challenges into transformative solutions that go beyond expectations. Tell us about your project, and we’ll provide the best solution with our collaborative and personalised approach to immune cell based assay development services.

RoukenBio | Immunology CRO redefined

Backed by our brilliant minds, we have turned the traditional CRO model on its head by fostering a collaborative and personalised approach to immune assay development.

Our mission is simple: Solve problems. Deliver quality data. Propel your drug discovery breakthroughs.

United by a passion to make sense of complexities and overcome challenges, we apply our specialised knowledge to big-picture thinking. We will explore every option to deliver over and above for your project.

We are thought leaders with a deep understanding of immunology, bioassays, molecular biology and a track record of groundbreaking discoveries and novel cell-based tools.

Hear from our clients

At RoukenBio, we stake our reputation on exceeding your expectations, as reflected in our world-class Net Promoter Score (NPS) of 79.
Our clients love working with us.

"Through multiple successful collaborations, RoukenBio has consistently delivered high quality, robust data. I highly recommend working with them!" Maya Kotturi, Ph.D | Executive Director of Translational Research | IGM BioSciences
"We initially reached out to RoukenBio 3 years ago to run intricate cell-based assays using primary immune cells; the company had come highly recommended by former colleagues. We were impressed right away by the depth of knowledge of the RoukenBio team and appreciated their input on our proposed experimental plans; the RoukenBio team excelled both at communicating and executing the work. I would highly recommend working with RoukenBio." Bijan Etemad-Gilbertson, Ph.D | Vice President of Antibody Technology | NextPoint Therapeutics
"We appreciate the consultative approach that RoukenBio uses, working closely with us to truly understand our needs prior to engaging. This model results in a highly customized offering, quick response times when challenges arise, and timely delivery of high-quality research services. Speed and reliability are important to us as we strive to create a healthier world through affordable biologic medicines." Dr. Claudia Wiza | Functional Assays Manager | AlvoTech